Selective inhibitors of trypanosomal uridylyl transferase RET1 establish druggability of RNA post-transcriptional modifications

Non-coding RNAs are crucial regulators for a vast array of cellular processes and have been implicated in human disease. These biological processes represent a hitherto untapped resource in our fight against disease. In this work we identify small molecule inhibitors of a non-coding RNA uridylylatio...

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Detalles Bibliográficos
Autores principales: Cording, Amy, Gormally, Michael, Bond, Peter J., Carrington, Mark, Balasubramanian, Shankar, Miska, Eric A., Thomas, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449093/
https://www.ncbi.nlm.nih.gov/pubmed/26786754
http://dx.doi.org/10.1080/15476286.2015.1137422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449093/
https://www.ncbi.nlm.nih.gov/pubmed/26786754
http://dx.doi.org/10.1080/15476286.2015.1137422

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