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Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model

Iron oxide nanoparticles (IONPs) are promising nanomaterials for biomedical applications. However, their inflammatory potential has not been fully established. Here, we used a lepirudin anti-coagulated human whole blood model to evaluate the potential of 10 nm IONPs to activate the complement system...

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Detalles Bibliográficos
Autores principales: Wolf-Grosse, Susann, Rokstad, Anne Mari, Ali, Syed, Lambris, John D, Mollnes, Tom E, Nilsen, Asbjørn M, Stenvik, Jørgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449102/
https://www.ncbi.nlm.nih.gov/pubmed/28579778
http://dx.doi.org/10.2147/IJN.S136453