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Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model
Iron oxide nanoparticles (IONPs) are promising nanomaterials for biomedical applications. However, their inflammatory potential has not been fully established. Here, we used a lepirudin anti-coagulated human whole blood model to evaluate the potential of 10 nm IONPs to activate the complement system...
Autores principales: | Wolf-Grosse, Susann, Rokstad, Anne Mari, Ali, Syed, Lambris, John D, Mollnes, Tom E, Nilsen, Asbjørn M, Stenvik, Jørgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449102/ https://www.ncbi.nlm.nih.gov/pubmed/28579778 http://dx.doi.org/10.2147/IJN.S136453 |
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