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Tumor necrosis factor α modulates sodium-activated potassium channel SLICK in rat dorsal horn neurons via p38 MAPK activation pathway

The dorsal horn (DH) of the spinal cord is the integrative center that processes and transmits pain sensation. Abnormal changes in ion channel expression can enhance the excitability of pain-related DH neurons. Sodium-activated potassium (K(Na)) channels are highly expressed particularly in the cent...

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Detalles Bibliográficos
Autores principales: Wang, Kun, Wang, Feng, Bao, Jun-Ping, Xie, Zhi-Yang, Chen, Lu, Zhou, Bao-Yi, Xie, Xin-Hui, Wu, Xiao-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449117/
https://www.ncbi.nlm.nih.gov/pubmed/28579824
http://dx.doi.org/10.2147/JPR.S132185