Cargando…

Bisdemethoxycurcumin in combination with α-PD-L1 antibody boosts immune response against bladder cancer

Curcumin was recently discovered to strengthen immune response through multiple mechanisms. Cytotoxic CD8(+) T-cells play a critical role in modulating anticancer immune response, but is severely restricted by T-cell exhaustion. Bladder carcinomas express PD-L1 and can abrogate CD8(+) T-cell respons...

Descripción completa

Detalles Bibliográficos
Autores principales: Shao, Yiqun, Zhu, Wenjing, Da, Jun, Xu, Mingxi, Wang, Yiwei, Zhou, Juan, Wang, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449128/
https://www.ncbi.nlm.nih.gov/pubmed/28579805
http://dx.doi.org/10.2147/OTT.S130653