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Bisdemethoxycurcumin in combination with α-PD-L1 antibody boosts immune response against bladder cancer
Curcumin was recently discovered to strengthen immune response through multiple mechanisms. Cytotoxic CD8(+) T-cells play a critical role in modulating anticancer immune response, but is severely restricted by T-cell exhaustion. Bladder carcinomas express PD-L1 and can abrogate CD8(+) T-cell respons...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449128/ https://www.ncbi.nlm.nih.gov/pubmed/28579805 http://dx.doi.org/10.2147/OTT.S130653 |