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Quantitative high-content imaging identifies novel regulators of Neo1 trafficking at endosomes

P4-ATPases are a family of putative phospholipid flippases that regulate lipid membrane asymmetry, which is important for vesicle formation. Two yeast flippases, Drs2 and Neo1, have nonredundant functions in the recycling of the synaptobrevin-like v-SNARE Snc1 from early endosomes. Drs2 activity is...

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Detalles Bibliográficos
Autores principales: Dalton, Lauren E., Bean, Björn D. M., Davey, Michael, Conibear, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449152/
https://www.ncbi.nlm.nih.gov/pubmed/28404745
http://dx.doi.org/10.1091/mbc.E16-11-0772