Aggregation is a critical cause of poor transfer into the brain tissue of intravenously administered cationic PAMAM dendrimer nanoparticles

Dendrimers have been expected as excellent nanodevices for brain medication. An amine-terminated polyamidoamine dendrimer (PD), an unmodified plain type of PD, has the obvious disadvantage of cytotoxicity, but still serves as an attractive molecule because it easily adheres to the cell surface, faci...

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Detalles Bibliográficos
Autores principales: Kurokawa, Yoshika, Sone, Hideko, Win-Shwe, Tin-Tin, Zeng, Yang, Kimura, Hiroyuki, Koyama, Yosuke, Yagi, Yusuke, Matsui, Yasuto, Yamazaki, Masashi, Hirano, Seishiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449168/
https://www.ncbi.nlm.nih.gov/pubmed/28579780
http://dx.doi.org/10.2147/IJN.S125808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449168/
https://www.ncbi.nlm.nih.gov/pubmed/28579780
http://dx.doi.org/10.2147/IJN.S125808

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