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The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling

Interaction between the nascent polypeptide chain and the ribosomal exit tunnel can modulate the rate of translation and induce translational arrest to regulate expression of downstream genes. The ribosomal tunnel also provides a protected environment for initial protein folding events. Here, we pre...

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Detalles Bibliográficos
Autores principales: Su, Ting, Cheng, Jingdong, Sohmen, Daniel, Hedman, Rickard, Berninghausen, Otto, von Heijne, Gunnar, Wilson, Daniel N, Beckmann, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449182/
https://www.ncbi.nlm.nih.gov/pubmed/28556777
http://dx.doi.org/10.7554/eLife.25642