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The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling
Interaction between the nascent polypeptide chain and the ribosomal exit tunnel can modulate the rate of translation and induce translational arrest to regulate expression of downstream genes. The ribosomal tunnel also provides a protected environment for initial protein folding events. Here, we pre...
Autores principales: | Su, Ting, Cheng, Jingdong, Sohmen, Daniel, Hedman, Rickard, Berninghausen, Otto, von Heijne, Gunnar, Wilson, Daniel N, Beckmann, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449182/ https://www.ncbi.nlm.nih.gov/pubmed/28556777 http://dx.doi.org/10.7554/eLife.25642 |
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