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Evidence for Widespread Degradation of Gene Control Regions in Hominid Genomes

Although sequences containing regulatory elements located close to protein-coding genes are often only weakly conserved during evolution, comparisons of rodent genomes have implied that these sequences are subject to some selective constraints. Evolutionary conservation is particularly apparent upst...

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Detalles Bibliográficos
Autores principales: Keightley, Peter D, Lercher, Martin J, Eyre-Walker, Adam
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544929/
https://www.ncbi.nlm.nih.gov/pubmed/15678168
http://dx.doi.org/10.1371/journal.pbio.0030042