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Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution

Amyloid β (Aβ) oligomers may play a decisive role in Alzheimer’s disease related neurodegeneration, but their structural properties are poorly understood. In this report, sedimentation velocity centrifugation, small angle neutron scattering (SANS) and molecular modelling were used to identify the sm...

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Detalles Bibliográficos
Autores principales: Wolff, Martin, Zhang-Haagen, Bo, Decker, Christina, Barz, Bogdan, Schneider, Mario, Biehl, Ralf, Radulescu, Aurel, Strodel, Birgit, Willbold, Dieter, Nagel-Steger, Luitgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449387/
https://www.ncbi.nlm.nih.gov/pubmed/28559586
http://dx.doi.org/10.1038/s41598-017-02370-3