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Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution
Amyloid β (Aβ) oligomers may play a decisive role in Alzheimer’s disease related neurodegeneration, but their structural properties are poorly understood. In this report, sedimentation velocity centrifugation, small angle neutron scattering (SANS) and molecular modelling were used to identify the sm...
Autores principales: | Wolff, Martin, Zhang-Haagen, Bo, Decker, Christina, Barz, Bogdan, Schneider, Mario, Biehl, Ralf, Radulescu, Aurel, Strodel, Birgit, Willbold, Dieter, Nagel-Steger, Luitgard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449387/ https://www.ncbi.nlm.nih.gov/pubmed/28559586 http://dx.doi.org/10.1038/s41598-017-02370-3 |
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