In silico analyses of deleterious missense SNPs of human apolipoprotein E3

ApoE3 is the major chylomicron apolipoprotein, binding in a specific liver peripheral cell receptor, allowing transport and normal catabolism of triglyceride-rich lipoprotein constituents. Point mutations in ApoE3 have been associated with Alzheimer’s disease, type III hyperlipoproteinemia, atherosc...

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Detalles Bibliográficos
Autores principales: Pires, Allan S., Porto, William F., Franco, Octavio L., Alencar, Sérgio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449402/
https://www.ncbi.nlm.nih.gov/pubmed/28559539
http://dx.doi.org/10.1038/s41598-017-01737-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449402/
https://www.ncbi.nlm.nih.gov/pubmed/28559539
http://dx.doi.org/10.1038/s41598-017-01737-w

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