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M2-like Kupffer cells in fibrotic liver may protect against acute insult

AIM: To investigate the mechanism of hepatoprotection conferred by liver fibrosis through evaluating the activation phenotype of kupffer cells. METHODS: Control and fibrotic mice were challenged with a lethal dose of D-GalN/lipopolysaccharide (LPS), and hepatic damage was assessed by histology, seru...

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Detalles Bibliográficos
Autores principales: Zheng, Qing-Fen, Bai, Li, Duan, Zhong-Ping, Han, Yuan-Ping, Zheng, Su-Jun, Chen, Yu, Li, Jian-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449422/
https://www.ncbi.nlm.nih.gov/pubmed/28611518
http://dx.doi.org/10.3748/wjg.v23.i20.3655