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Immunogenicity and Protective Efficacy of a Fusion Protein Tuberculosis Vaccine Combining Five Esx Family Proteins

One strategy to develop the next generation of tuberculosis vaccines is to construct subunit vaccines based on T cell antigens. In this study, we have evaluated the vaccine potential of a fusion protein combining EsxB, EsxD, EsxG, EsxU, and EsxM of Mycobacterium tuberculosis (M. tb). This recombinan...

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Detalles Bibliográficos
Autores principales: Xiang, Zhi-hao, Sun, Rui-feng, Lin, Chen, Chen, Fu-zeng, Mai, Jun-tao, Liu, Yu-xiao, Xu, Zi-yan, Zhang, Lu, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449442/
https://www.ncbi.nlm.nih.gov/pubmed/28620588
http://dx.doi.org/10.3389/fcimb.2017.00226