Anti-Double-Stranded DNA IgG Participates in Renal Fibrosis through Suppressing the Suppressor of Cytokine Signaling 1 Signals

Suppressor of cytokine signaling 1 (SOCS1) participates in renal fibrosis by downregulating Janus kinase 2 (JAK2)/signal transducer and activator of transcription 1 (STAT1)-mediated cytokine signaling. Recently, it was found that anti-double-stranded DNA (dsDNA) IgG induces the synthesis of profibro...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Yang, Jie, Tong, Fang, Duan, Zhaoyang, Liu, Xingyin, Xia, Linlin, Li, Ke, Xia, Yumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449454/
https://www.ncbi.nlm.nih.gov/pubmed/28620377
http://dx.doi.org/10.3389/fimmu.2017.00610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449454/
https://www.ncbi.nlm.nih.gov/pubmed/28620377
http://dx.doi.org/10.3389/fimmu.2017.00610

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