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Oral Administration of a Seed-based Bivalent Rotavirus Vaccine Containing VP6 and NSP4 Induces Specific Immune Responses in Mice

Rotavirus is the leading cause of severe diarrheal disease among newborns. Plant-based rotavirus vaccines have been developed in recent years and have been proven to be effective in animal models. In the present study, we report a bivalent vaccine candidate expressing rotavirus subunits VP6 and NSP4...

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Detalles Bibliográficos
Autores principales: Feng, Hao, Li, Xin, Song, Weibin, Duan, Mei, Chen, Hong, Wang, Tao, Dong, Jiangli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449476/
https://www.ncbi.nlm.nih.gov/pubmed/28620404
http://dx.doi.org/10.3389/fpls.2017.00910