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Expression of Class I and Class II a/b Histone Deacetylase is Dysregulated in Hypertensive Animal Models

BACKGROUND AND OBJECTIVES: Dysregulation of histone deacetylase expression and enzymatic activity is associated with a number of diseases. It has been reported that protein levels of histone deacetylase (HDAC)1 and HDAC5 increase during human pulmonary hypertension, and that the enzymatic activity o...

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Detalles Bibliográficos
Autores principales: Kee, Hae Jin, Kim, Gwi Ran, Lin, Ming Quan, Choi, Sin Young, Ryu, Yuhee, Jin, Li, Piao, Zhe Hao, Jeong, Myung Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Cardiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449534/
https://www.ncbi.nlm.nih.gov/pubmed/28567090
http://dx.doi.org/10.4070/kcj.2016.0266