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The Yin and Yang of bile acid action on tight junctions in a model colonic epithelium

Gastrointestinal epithelial barrier loss due to tight junction (TJ) dysfunction and bile acid‐induced diarrhea are common in patients with inflammatory diseases. Although excess colonic bile acids are known to alter mucosal permeability, few studies have compared the effects of specific bile acids o...

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Detalles Bibliográficos
Autores principales: Sarathy, Jayashree, Detloff, Sally Jo, Ao, Mei, Khan, Nabihah, French, Sydney, Sirajuddin, Hafsa, Nair, Tanushree, Rao, Mrinalini C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449568/
https://www.ncbi.nlm.nih.gov/pubmed/28554966
http://dx.doi.org/10.14814/phy2.13294