Are zinc-bound metallothionein isoforms (I+II and III) involved in impaired thymulin production and thymic involution during ageing?

BACKGROUND: With advancing age, thymic efficiency shows progressive decline due to thymic involution allowing impaired cell-mediated immunity and the appearance of age-related diseases. The intrinsic cause of thymic involution is still undefined. Chronic inflammation and high glucocorticoids (GCs) m...

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Detalles Bibliográficos
Autores principales: Mocchegiani, Eugenio, Giacconi, Robertina, Cipriano, Catia, Muti, Elisa, Gasparini, Nazzarena, Malavolta, Marco
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544958/
https://www.ncbi.nlm.nih.gov/pubmed/15679929
http://dx.doi.org/10.1186/1742-4933-1-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544958/
https://www.ncbi.nlm.nih.gov/pubmed/15679929
http://dx.doi.org/10.1186/1742-4933-1-5

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