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Synthesis and polymerase activity of a fluorescent cytidine TNA triphosphate analogue
Threose nucleic acid (TNA) is an artificial genetic polymer capable of undergoing Darwinian evolution to produce aptamers with affinity to specific targets. This property, coupled with a backbone structure that is refractory to nuclease digestion, makes TNA an attractive biopolymer system for diagno...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449585/ https://www.ncbi.nlm.nih.gov/pubmed/28472363 http://dx.doi.org/10.1093/nar/gkx368 |