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Synthesis and polymerase activity of a fluorescent cytidine TNA triphosphate analogue

Threose nucleic acid (TNA) is an artificial genetic polymer capable of undergoing Darwinian evolution to produce aptamers with affinity to specific targets. This property, coupled with a backbone structure that is refractory to nuclease digestion, makes TNA an attractive biopolymer system for diagno...

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Detalles Bibliográficos
Autores principales: Mei, Hui, Shi, Changhua, Jimenez, Randi M., Wang, Yajun, Kardouh, Miramar, Chaput, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449585/
https://www.ncbi.nlm.nih.gov/pubmed/28472363
http://dx.doi.org/10.1093/nar/gkx368