The SWI/SNF ATP-dependent nucleosome remodeler promotes resection initiation at a DNA double-strand break in yeast

DNA double-strand breaks (DSBs) are repaired by either the non-homologous end joining (NHEJ) or homologous recombination (HR) pathway. Pathway choice is determined by the generation of 3΄ single-strand DNA overhangs at the break that are initiated by the action of the Mre11–Rad50–Xrs2 (MRX) complex...

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Detalles Bibliográficos
Autores principales: Wiest, Nathaniel E., Houghtaling, Scott, Sanchez, Joseph C., Tomkinson, Alan E., Osley, Mary Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449591/
https://www.ncbi.nlm.nih.gov/pubmed/28398510
http://dx.doi.org/10.1093/nar/gkx221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449591/
https://www.ncbi.nlm.nih.gov/pubmed/28398510
http://dx.doi.org/10.1093/nar/gkx221

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