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The dynamics of the monomeric restriction endonuclease BcnI during its interaction with DNA

Endonucleases that generate DNA double strand breaks often employ two independent subunits such that the active site from each subunit cuts either DNA strand. Restriction enzyme BcnI is a remarkable exception. It binds to the 5΄-CC/SGG-3΄ (where S = C or G, ‘/’ designates the cleavage position) targ...

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Detalles Bibliográficos
Autores principales: Kostiuk, Georgij, Dikić, Jasmina, Schwarz, Friedrich W., Sasnauskas, Giedrius, Seidel, Ralf, Siksnys, Virginijus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449598/
https://www.ncbi.nlm.nih.gov/pubmed/28453854
http://dx.doi.org/10.1093/nar/gkx294