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Genome urbanization: clusters of topologically co-regulated genes delineate functional compartments in the genome of Saccharomyces cerevisiae

The eukaryotic genome evolves under the dual constraint of maintaining coordinated gene transcription and performing effective DNA replication and cell division, the coupling of which brings about inevitable DNA topological tension. DNA supercoiling is resolved and, in some cases, even harnessed by...

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Detalles Bibliográficos
Autores principales: Tsochatzidou, Maria, Malliarou, Maria, Papanikolaou, Nikolas, Roca, Joaquim, Nikolaou, Christoforos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449599/
https://www.ncbi.nlm.nih.gov/pubmed/28369650
http://dx.doi.org/10.1093/nar/gkx198