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N (6)-methyladenosine alters RNA structure to regulate binding of a low-complexity protein

N (6)-methyladenosine (m(6)A) is the most abundant internal modification in eukaryotic messenger RNA (mRNA), and affects almost every stage of the mRNA life cycle. The YTH-domain proteins can specifically recognize m(6)A modification to control mRNA maturation, translation and decay. m(6)A can also...

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Detalles Bibliográficos
Autores principales: Liu, Nian, Zhou, Katherine I., Parisien, Marc, Dai, Qing, Diatchenko, Luda, Pan, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449601/
https://www.ncbi.nlm.nih.gov/pubmed/28334903
http://dx.doi.org/10.1093/nar/gkx141