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N (6)-methyladenosine alters RNA structure to regulate binding of a low-complexity protein
N (6)-methyladenosine (m(6)A) is the most abundant internal modification in eukaryotic messenger RNA (mRNA), and affects almost every stage of the mRNA life cycle. The YTH-domain proteins can specifically recognize m(6)A modification to control mRNA maturation, translation and decay. m(6)A can also...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449601/ https://www.ncbi.nlm.nih.gov/pubmed/28334903 http://dx.doi.org/10.1093/nar/gkx141 |