Cargando…

N (6)-methyladenosine alters RNA structure to regulate binding of a low-complexity protein

N (6)-methyladenosine (m(6)A) is the most abundant internal modification in eukaryotic messenger RNA (mRNA), and affects almost every stage of the mRNA life cycle. The YTH-domain proteins can specifically recognize m(6)A modification to control mRNA maturation, translation and decay. m(6)A can also...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Nian, Zhou, Katherine I., Parisien, Marc, Dai, Qing, Diatchenko, Luda, Pan, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449601/ https://www.ncbi.nlm.nih.gov/pubmed/28334903 http://dx.doi.org/10.1093/nar/gkx141

Ejemplares similares

Identification of recognition residues for ligation-based detection and quantitation of pseudouridine and N(6)-methyladenosine
por: Dai, Qing, et al.
Publicado: (2007)

N(6)-methyladenosine-dependent RNA structural switches regulate RNA-protein interactions
por: Liu, Nian, et al.
Publicado: (2015)

Widespread occurrence of N(6)-methyladenosine in bacterial mRNA
por: Deng, Xin, et al.
Publicado: (2015)

Solution structure of the YTH domain in complex with N6-methyladenosine RNA: a reader of methylated RNA
por: Theler, Dominik, et al.
Publicado: (2014)

Probing N(6)-methyladenosine RNA modification status at single nucleotide resolution in mRNA and long noncoding RNA
por: Liu, Nian, et al.
Publicado: (2013)

Disruptive mRNA folding increases translational efficiency of catechol-O-methyltransferase variant
por: Tsao, Douglas, et al.
Publicado: (2011)

N (6)-methyladenosine modification and METTL3 modulate enterovirus 71 replication
por: Hao, Haojie, et al.
Publicado: (2019)

The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent
por: Hauenschild, Ralf, et al.
Publicado: (2015)

Genetic studies of human neuropathic pain conditions: a review
por: Zorina-Lichtenwalter, Katerina, et al.
Publicado: (2018)

N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing
por: Bartosovic, Marek, et al.
Publicado: (2017)

Omics approaches to discover pathophysiological pathways contributing to human pain
por: Diatchenko, Luda, et al.
Publicado: (2022)

A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding
por: Stowell, James A. W., et al.
Publicado: (2018)

Chronic pain and premature mortality in men and women, using data from UK Biobank. Reply.
por: Parisien, Marc, et al.
Publicado: (2023)

N- and C-terminal Upf1 phosphorylations create binding platforms for SMG-6 and SMG-5:SMG-7 during NMD
por: Okada-Katsuhata, Yukiko, et al.
Publicado: (2012)

Discovery of the β-barrel–type RNA methyltransferase responsible for N(6)-methylation of N(6)-threonylcarbamoyladenosine in tRNAs
por: Kimura, Satoshi, et al.
Publicado: (2014)

The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing
por: McGrail, Joanne C., et al.
Publicado: (2009)

Rapid binding and release of Hfq from ternary complexes during RNA annealing
por: Hopkins, Julia F., et al.
Publicado: (2011)

Involvement of the nuclear cap-binding protein complex in alternative splicing in Arabidopsis thaliana
por: Raczynska, Katarzyna Dorota, et al.
Publicado: (2010)

A hydantoin isoform of cyclic N(6)-threonylcarbamoyladenosine (ct(6)A) is present in tRNAs
por: Matuszewski, Michal, et al.
Publicado: (2017)

On the availability of microRNA-induced silencing complexes, saturation of microRNA-binding sites and stoichiometry
por: Mayya, Vinay K., et al.
Publicado: (2015)

CRISPR RNA binding and DNA target recognition by purified Cascade complexes from Escherichia coli
por: Beloglazova, Natalia, et al.
Publicado: (2015)

tRNA over-expression in breast cancer and functional consequences
por: Pavon-Eternod, Mariana, et al.
Publicado: (2009)

Alternative Splicing of Opioid Receptor Genes Shows a Conserved Pattern for 6TM Receptor Variants
por: Piltonen, Marjo, et al.
Publicado: (2020)

Translation-competent 48S complex formation on HCV IRES requires the RNA-binding protein NSAP1
por: Park, Sung Mi, et al.
Publicado: (2011)

SECIS-binding protein 2 interacts with the SMN complex and the methylosome for selenoprotein mRNP assembly and translation
por: Gribling-Burrer, Anne-Sophie, et al.
Publicado: (2017)

The RNA-binding domain of influenzavirus non-structural protein-1 cooperatively binds to virus-specific RNA sequences in a structure-dependent manner
por: Marc, Daniel, et al.
Publicado: (2013)

Unraveling the structural complexity in a single-stranded RNA tail: implications for efficient ligand binding in the prequeuosine riboswitch
por: Eichhorn, Catherine D., et al.
Publicado: (2012)

A dsRNA-binding protein of a complex invertebrate DNA virus suppresses the Drosophila RNAi response
por: Bronkhorst, Alfred W., et al.
Publicado: (2014)

The human translation initiation multi-factor complex promotes methionyl-tRNA(i) binding to the 40S ribosomal subunit
por: Sokabe, Masaaki, et al.
Publicado: (2012)

The Lsm2-8 complex determines nuclear localization of the spliceosomal U6 snRNA
por: Spiller, Michael P., et al.
Publicado: (2007)

Trypanosome RNAEditing Substrate Binding Complex integrity and function depends on the upstream action of RESC10
por: Dubey, Ashutosh P, et al.
Publicado: (2021)

EBP1 and DRBP76/NF90 binding proteins are included in the major histocompatibility complex class II RNA operon
por: Corso, Carmela, et al.
Publicado: (2011)

RBM7 subunit of the NEXT complex binds U-rich sequences and targets 3′-end extended forms of snRNAs
por: Hrossova, Dominika, et al.
Publicado: (2015)

NUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins
por: Bizarro, Jonathan, et al.
Publicado: (2015)

Functional assignment of KEOPS/EKC complex subunits in the biosynthesis of the universal t(6)A tRNA modification
por: Perrochia, Ludovic, et al.
Publicado: (2013)

Amino acid residues critical for RNA-binding in the N-terminal domain of the nucleocapsid protein are essential determinants for the infectivity of coronavirus in cultured cells
por: Tan, Yong Wah, et al.
Publicado: (2006)

Air2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activation
por: Holub, Peter, et al.
Publicado: (2012)

Rare variant analyses in large-scale cohorts identified SLC13A1 associated with chronic pain
por: Ao, Xiang, et al.
Publicado: (2023)

Coordination of two sequential ester-transfer reactions: exogenous guanosine binding promotes the subsequent ωG binding to a group I intron
por: Bao, Penghui, et al.
Publicado: (2008)

Pentamidine binds to tRNA through non-specific hydrophobic interactions and inhibits aminoacylation and translation
por: Sun, Tao, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_voklmt8ochlssu606h4ipkshi1