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Structural and mechanistic insights into regulation of HBO1 histone acetyltransferase activity by BRPF2

HBO1, a member of the MYST family of histone acetyltransferases (HATs), is required for global acetylation of histone H3K14 and embryonic development. It functions as a catalytic subunit in multisubunit complexes comprising a BRPF1/2/3 or JADE1/2/3 scaffold protein, and two accessory proteins. BRPF2...

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Detalles Bibliográficos
Autores principales: Tao, Ye, Zhong, Chen, Zhu, Junjun, Xu, Shutong, Ding, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449618/
https://www.ncbi.nlm.nih.gov/pubmed/28334966
http://dx.doi.org/10.1093/nar/gkx142