Removing bias against short sequences enables northern blotting to better complement RNA-seq for the study of small RNAs

Changes in small non-coding RNAs such as micro RNAs (miRNAs) can serve as indicators of disease and can be measured using next-generation sequencing of RNA (RNA-seq). Here, we highlight the need for approaches that complement RNA-seq, discover that northern blotting of small RNAs is biased against s...

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Detalles Bibliográficos
Autores principales: Choi, Yun S., Edwards, Lanelle O., DiBello, Aubrey, Jose, Antony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449620/
https://www.ncbi.nlm.nih.gov/pubmed/28180294
http://dx.doi.org/10.1093/nar/gkx091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449620/
https://www.ncbi.nlm.nih.gov/pubmed/28180294
http://dx.doi.org/10.1093/nar/gkx091

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