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A branch-migration based fluorescent probe for straightforward, sensitive and specific discrimination of DNA mutations
Genetic mutations are important biomarkers for cancer diagnostics and surveillance. Preferably, the methods for mutation detection should be straightforward, highly specific and sensitive to low-level mutations within various sequence contexts, fast and applicable at room-temperature. Though some of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449635/ https://www.ncbi.nlm.nih.gov/pubmed/28201758 http://dx.doi.org/10.1093/nar/gkx117 |