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A branch-migration based fluorescent probe for straightforward, sensitive and specific discrimination of DNA mutations

Genetic mutations are important biomarkers for cancer diagnostics and surveillance. Preferably, the methods for mutation detection should be straightforward, highly specific and sensitive to low-level mutations within various sequence contexts, fast and applicable at room-temperature. Though some of...

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Detalles Bibliográficos
Autores principales: Xiao, Xianjin, Wu, Tongbo, Xu, Lei, Chen, Wei, Zhao, Meiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449635/
https://www.ncbi.nlm.nih.gov/pubmed/28201758
http://dx.doi.org/10.1093/nar/gkx117