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Stabilization of RNA hairpins using non-nucleotide linkers and circularization

An RNA hairpin is an essential structural element of RNA. Hairpins play crucial roles in gene expression and intermolecular recognition but are also involved in the pathogenesis of some congenital diseases. Structural studies of the hairpin motifs are impeded by their thermodynamic instability, as t...

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Detalles Bibliográficos
Autores principales: Kiliszek, Agnieszka, Błaszczyk, Leszek, Kierzek, Ryszard, Rypniewski, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449636/
https://www.ncbi.nlm.nih.gov/pubmed/28334744
http://dx.doi.org/10.1093/nar/gkx122