A Toxin Involved in Salmonella Persistence Regulates Its Activity by Acetylating Its Cognate Antitoxin, a Modification Reversed by CobB Sirtuin Deacetylase

Bacterial toxin-antitoxin systems trigger the onset of a persister state by inhibiting essential cellular processes. The TacT toxin of Salmonella enterica is known to induce a persister state in macrophages through the acetylation of aminoacyl-tRNAs. Here, we show that the TacT toxin and the TacA an...

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Detalles Bibliográficos
Autores principales: VanDrisse, Chelsey M., Parks, Anastacia R., Escalante-Semerena, Jorge C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449658/
https://www.ncbi.nlm.nih.gov/pubmed/28559487
http://dx.doi.org/10.1128/mBio.00708-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449658/
https://www.ncbi.nlm.nih.gov/pubmed/28559487
http://dx.doi.org/10.1128/mBio.00708-17

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