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Single-Cell mRNA Sequencing in Cancer Research: Integrating the Genomic Fingerprint
Critical cancer mutations are often regional and mosaic, confounding the efficacy of targeted therapeutics. Single cell mRNA sequencing (scRNA-seq) has enabled unprecedented studies of intra-tumor heterogeneity and its role in cancer progression, metastasis, and treatment resistance. When coupled wi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450061/ https://www.ncbi.nlm.nih.gov/pubmed/28620412 http://dx.doi.org/10.3389/fgene.2017.00073 |