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High-throughput validation of ceRNA regulatory networks

BACKGROUND: MicroRNAs (miRNAs) play multiple roles in tumor biology. Interestingly, reports from multiple groups suggest that miRNA targets may be coupled through competitive stoichiometric sequestration. Specifically, computational models predicted and experimental assays confirmed that miRNA activ...

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Detalles Bibliográficos
Autores principales: Chiu, Hua-Sheng, Martínez, María Rodríguez, Bansal, Mukesh, Subramanian, Aravind, Golub, Todd R., Yang, Xuerui, Sumazin, Pavel, Califano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450082/
https://www.ncbi.nlm.nih.gov/pubmed/28558729
http://dx.doi.org/10.1186/s12864-017-3790-7