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High-throughput validation of ceRNA regulatory networks
BACKGROUND: MicroRNAs (miRNAs) play multiple roles in tumor biology. Interestingly, reports from multiple groups suggest that miRNA targets may be coupled through competitive stoichiometric sequestration. Specifically, computational models predicted and experimental assays confirmed that miRNA activ...
Autores principales: | Chiu, Hua-Sheng, Martínez, María Rodríguez, Bansal, Mukesh, Subramanian, Aravind, Golub, Todd R., Yang, Xuerui, Sumazin, Pavel, Califano, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450082/ https://www.ncbi.nlm.nih.gov/pubmed/28558729 http://dx.doi.org/10.1186/s12864-017-3790-7 |
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