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HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex difference
BACKGROUND: Sexual difference has been shown in the pathogenesis of chronic kidney disease induced by hypertension. Females are protected from hypertension and related end-organ damage. Augmentation of renal proximal tubular angiotensinogen (AGT) expression can promote intrarenal angiotensin formati...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450130/ https://www.ncbi.nlm.nih.gov/pubmed/28572913 http://dx.doi.org/10.1186/s13293-017-0140-z |