Extracellular heat shock protein 90α mediates HDM-induced bronchial epithelial barrier dysfunction by activating RhoA/MLC signaling

BACKGROUND: The disruption and hyperpermeability of bronchial epithelial barrier are closely related to the pathogenesis of asthma. House dust mite (HDM), one of the most important allergens, could increase the airway epithelial permeability. Heat shock protein (Hsp) 90α is also implicated in the lu...

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Detalles Bibliográficos
Autores principales: Dong, Hang-ming, Le, Yan-qing, Wang, Yan-hong, Zhao, Hai-jin, Huang, Chao-wen, Hu, Ya-hui, Luo, Li-shan, Wan, Xuan, Wei, Yi-lan, Chu, Zi-qiang, Li, Wei, Cai, Shao-xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450201/
https://www.ncbi.nlm.nih.gov/pubmed/28558721
http://dx.doi.org/10.1186/s12931-017-0593-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450201/
https://www.ncbi.nlm.nih.gov/pubmed/28558721
http://dx.doi.org/10.1186/s12931-017-0593-y

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