Cargando…

Predicting the targeting of tail-anchored proteins to subcellular compartments in mammalian cells

Tail-anchored (TA) proteins contain a single transmembrane domain (TMD) at the C-terminus that anchors them to the membranes of organelles where they mediate critical cellular processes. Accordingly, mutations in genes encoding TA proteins have been identified in a number of severe inherited disorde...

Descripción completa

Detalles Bibliográficos
Autores principales: Costello, Joseph L., Castro, Inês G., Camões, Fátima, Schrader, Tina A., McNeall, Doug, Yang, Jing, Giannopoulou, Evdokia-Anastasia, Gomes, Sílvia, Pogenberg, Vivian, Bonekamp, Nina A., Ribeiro, Daniela, Wilmanns, Matthias, Jedd, Gregory, Islinger, Markus, Schrader, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450235/
https://www.ncbi.nlm.nih.gov/pubmed/28325759
http://dx.doi.org/10.1242/jcs.200204