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Genome-wide network-based pathway analysis of CSF t-tau/Aβ1-42 ratio in the ADNI cohort

BACKGROUND: The cerebrospinal fluid (CSF) levels of total tau (t-tau) and Aβ(1–42) are potential early diagnostic markers for probable Alzheimer’s disease (AD). The influence of genetic variation on these CSF biomarkers has been investigated in candidate or genome-wide association studies (GWAS). Ho...

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Detalles Bibliográficos
Autores principales: Cong, Wang, Meng, Xianglian, Li, Jin, Zhang, Qiushi, Chen, Feng, Liu, Wenjie, Wang, Ying, Cheng, Sipu, Yao, Xiaohui, Yan, Jingwen, Kim, Sungeun, Saykin, Andrew J., Liang, Hong, Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450240/
https://www.ncbi.nlm.nih.gov/pubmed/28558704
http://dx.doi.org/10.1186/s12864-017-3798-z