Calpain mobilizes Atg9/Bif-1 vesicles from Golgi stacks upon autophagy induction by thapsigargin

CAPNS1 is essential for stability and function of the ubiquitous calcium-dependent proteases micro- and milli-calpain. Upon inhibition of the endoplasmic reticulum Ca(2+) ATPase by 100 nM thapsigargin, both micro-calpain and autophagy are activated in human U2OS osteosarcoma cells in a CAPNS1-depend...

Descripción completa

Detalles Bibliográficos
Autores principales: Marcassa, Elena, Raimondi, Marzia, Anwar, Tahira, Eskelinen, Eeva-Liisa, Myers, Michael P., Triolo, Gianluca, Schneider, Claudio, Demarchi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450315/
https://www.ncbi.nlm.nih.gov/pubmed/28302665
http://dx.doi.org/10.1242/bio.022806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450315/
https://www.ncbi.nlm.nih.gov/pubmed/28302665
http://dx.doi.org/10.1242/bio.022806

Ejemplares similares