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Calpain mobilizes Atg9/Bif-1 vesicles from Golgi stacks upon autophagy induction by thapsigargin

CAPNS1 is essential for stability and function of the ubiquitous calcium-dependent proteases micro- and milli-calpain. Upon inhibition of the endoplasmic reticulum Ca(2+) ATPase by 100 nM thapsigargin, both micro-calpain and autophagy are activated in human U2OS osteosarcoma cells in a CAPNS1-depend...

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Detalles Bibliográficos
Autores principales:	Marcassa, Elena, Raimondi, Marzia, Anwar, Tahira, Eskelinen, Eeva-Liisa, Myers, Michael P., Triolo, Gianluca, Schneider, Claudio, Demarchi, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450315/ https://www.ncbi.nlm.nih.gov/pubmed/28302665 http://dx.doi.org/10.1242/bio.022806

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