Cargando…

Reduced β-catenin expression affects patterning of bone primordia, but not bone maturation

Wnt/β-catenin signaling is involved in patterning of bone primordia, but also plays an important role in the differentiation of chondrocytes and osteoblasts. During these processes the level of β-catenin must be tightly regulated. Excess β-catenin leads to conditions with increased bone mass, wherea...

Descripción completa

Detalles Bibliográficos
Autores principales: Pflug, Tobias, Huynh-Do, Uyen, Rudloff, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450319/
https://www.ncbi.nlm.nih.gov/pubmed/28347990
http://dx.doi.org/10.1242/bio.023572