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A novel proteolytic event controls Hedgehog intracellular sorting and distribution to receptive fields

The patterning activity of a morphogen depends on secretion and dispersal mechanisms that shape its distribution to the cells of a receptive field. In the case of the protein Hedgehog (Hh), these mechanisms of secretion and transmission remain unclear. In the developing Drosophila visual system, Hh...

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Detalles Bibliográficos
Autores principales: Daniele, Joseph R., Chu, Tehyen, Kunes, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450321/
https://www.ncbi.nlm.nih.gov/pubmed/28298318
http://dx.doi.org/10.1242/bio.024083