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Interleukin-6 Deficiency Attenuates Retinal Ganglion Cell Axonopathy and Glaucoma-Related Vision Loss

The pleotropic cytokine interleukin-6 (IL-6) is implicated in retinal ganglion cell (RGC) survival and degeneration, including that associated with glaucoma. IL-6 protects RGCs from pressure-induced apoptosis in vitro. However, it is unknown how IL-6 impacts glaucomatous degeneration in vivo. To stu...

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Detalles Bibliográficos
Autores principales: Echevarria, Franklin D., Formichella, Cathryn R., Sappington, Rebecca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450377/
https://www.ncbi.nlm.nih.gov/pubmed/28620279
http://dx.doi.org/10.3389/fnins.2017.00318