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APOBEC3B, a molecular driver of mutagenesis in human cancers
Human cancers results in large part from the accumulation of multiple mutations. The progression of premalignant cells is an evolutionary process in which mutations provide the fundamental driving force for genetic diversity. The increased mutation rate in premalignant cells allows selection for inc...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450379/ https://www.ncbi.nlm.nih.gov/pubmed/28572915 http://dx.doi.org/10.1186/s13578-017-0156-4 |