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APOBEC3B, a molecular driver of mutagenesis in human cancers

Human cancers results in large part from the accumulation of multiple mutations. The progression of premalignant cells is an evolutionary process in which mutations provide the fundamental driving force for genetic diversity. The increased mutation rate in premalignant cells allows selection for inc...

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Detalles Bibliográficos
Autores principales: Zou, Jun, Wang, Chen, Ma, Xiangyi, Wang, Edward, Peng, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450379/
https://www.ncbi.nlm.nih.gov/pubmed/28572915
http://dx.doi.org/10.1186/s13578-017-0156-4

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