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Combination of Helicobacter pylori infection and the interleukin 8 –251 T > A polymorphism, but not the mannose-binding lectin 2 codon 54 G > A polymorphism, might be a risk factor of gastric cancer

BACKGROUND: Mannose-binding lectin (MBL) acts in the innate immune response to Helicobacter pylori. Interleukin 8 (IL-8) is a potent cytokine produced by gastric epithelial cells in response to H. pylori. We aimed to investigate whether polymorphisms in MBL2 and IL-8 influence susceptibility to H. p...

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Detalles Bibliográficos
Autores principales: Chang, Young Woon, Oh, Chi Hyuk, Kim, Jung-Wook, Lee, Jae Won, Park, Mi Ju, Shim, Jae-Jun, Lee, Chang Kyun, Jang, Jae-Young, Dong, Seok Ho, Kim, Hyo Jong, Kim, Sung Soo, Kim, Byung-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450387/
https://www.ncbi.nlm.nih.gov/pubmed/28558668
http://dx.doi.org/10.1186/s12885-017-3378-2