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Sex differences in the development of vascular and renal lesions in mice with a simultaneous deficiency of Apoe and the integrin chain Itga8

BACKGROUND: Apoe-deficient (Apoe (−/−)) mice develop progressive atherosclerotic lesions with age but no severe renal pathology in the absence of additional challenges. We recently described accelerated atherosclerosis as well as marked renal injury in Apoe (−/−) mice deficient in the mesenchymal in...

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Detalles Bibliográficos
Autores principales: Marek, Ines, Canu, Maurizio, Cordasic, Nada, Rauh, Manfred, Volkert, Gudrun, Fahlbusch, Fabian B., Rascher, Wolfgang, Hilgers, Karl F., Hartner, Andrea, Menendez-Castro, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450388/
https://www.ncbi.nlm.nih.gov/pubmed/28572914
http://dx.doi.org/10.1186/s13293-017-0141-y